Search for a specific protein

Description:

Profile of the selected protein (log2)

The fold change is calculated by dividing the mean relative abundance of each condition in which specific DUBs were added by the mean relative abundance of the control (NO DUB) within the same experiment.

Relative abundance profile of the selected protein

Log2 profile of the closest proteins

Heatmap of proteins with similar profile

(Clustering is not applicable due to the presence of missing values.)

Log2 profile of the closest proteins

Heatmap of proteins with similar profile

(Clustering is not applicable due to the possible presence of missing values.)

Select a DUB from an experiment:

*The t-test will be only re-run after clicking the button.
*Changes only the area of red box. Does not change results of t-test.

List of all the proteins detected in the experiment

Candidate DUB substrates

Two-way hierarchical cluster analysis based on the activity of each DUB against the proteins found in all ten experiments (common set of proteins)
**Orange boxes: candidate DUB substrates. **Purple boxes: non-substrates. **To see protein names use the hover tool at the right top corner.
Input the fold change cut off to set the color scale of the heatmap for a prefered look.
If missing values are included only the columns are clustered.
To see protein names use the hover tool at the right top corner.